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Comparison of Performance of Quantitative ADC versus PI-RADS v2 Assessment for Differentiating High-grade from Low-grade Prostate Cancer

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publication Date:
May-2016
Citation:
The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P6262.
Appears in Collections:
ISMRM
Sponsors:
U01 CA151261/CA/NCI NIH HHS/United States
R25 CA089017/CA/NCI NIH HHS/United States
P41 EB015898/EB/NIBIB NIH HHS/United States
Generated Citation:
Hassanzadeh E., Olubiyi O.I., Fedorov A., Glazer D.I., Tempany C.M., Fennessy F.M. Comparison of Performance of Quantitative ADC versus PI-RADS v2 Assessment for Differentiating High-grade from Low-grade Prostate Cancer. The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P6262.
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One of the challenges in prostate cancer (PCa) management is the ability to differentiate aggressive tumors that require prompt treatment from indolent tumors that can safely undergo active surveillance. To promote global standardization and diminish variation in the acquisition, interpretation, and reporting of prostate multi-parametric MRI (mpMRI) examinations, Prostate Imaging Reporting and Data System (PI-RADS) has been introduced. The second version of PI-RADS (PI-RADS v2) was released early in 2015, but requires clinical validation. Here, we present the results of a study investigating the performance of PI-RADS v2 compared to quantitative ADC (qADC) values in discriminate high-grade from low-grade PCa.