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In-Bore MRI-Guided Transperineal Prostate Biopsy using 4-DOF Needle-Guide Manipulator

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publication Date:
May-2016
Citation:
The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P825.
Appears in Collections:
ISMRM
Sponsors:
R01 CA111288/CA/NCI NIH HHS/United States
R01 EB020667/EB/NIBIB NIH HHS/United States
P41 EB015898/EB/NIBIB NIH HHS/United States
Generated Citation:
Tokuda J., Tuncali K., Li G., Patel N., Heffter T., Fischer G.S., Iordachita I., Burdette E.C., Hata N., Tempany C.M. In-Bore MRI-Guided Transperineal Prostate Biopsy using 4-DOF Needle-Guide Manipulator. The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P825.
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We present the clinical feasibility of our MRI-compatible 4-DOF needle-guide manipulator for in-bore MRI-guided transperineal prostate biopsy. Total 11 men were biopsied in a 3T MRI scanner using this manipulator. All 11 procedures were successfully performed in 102.6±24.5 minutes with targeting errors of 4.9±2.9 mm. The targeting errors were consistent with other clinical studies. Pathology results confirmed prostate cancer with Gleason score ≥ 6 in 5/6 men with previous negative TRUS biopsies, and upgraded 2/5 men on active surveillance to clinically significant cancer with Gleason score 7. In conclusion, In-bore MRI-guided prostate biopsy using the manipulator was feasible.