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Evaluation of R2*-based Temperature Mapping for Predicting the Kill Zone in MRI-guided Renal Cryoablation

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publication Date:
May-2016
Citation:
The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P4564.
Appears in Collections:
ISMRM
Sponsors:
P41 EB015898/EB/NIBIB NIH HHS/United States
Generated Citation:
Tokuda J., Tuncali K., Kok L., Levesque V.M., Seethamraju R.T., Tempany C.M., Schmidt E.J. Evaluation of R2*-based Temperature Mapping for Predicting the Kill Zone in MRI-guided Renal Cryoablation. The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P4564.
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We tested the feasibility of R2*-based temperature mapping using a PETRA UTE sequence to determine the “kill zone” within an ice ball in the kidney during MRI-guided renal cryoablation. R2*-maps were calculated from dual-echo PETRA images acquired during six renal cryoablation cases, and converted to temperature maps using R2*-temperature calibrations performed in swine kidneys. We compared ablation volumes estimated from (a) the -20°C boundary on the temperature maps; (b) the signal void on intra-procedural T2-weighted images; and (c) post-ablation contrast- enhanced MRI as the “gold standard”. Results show that R2*-based temperature maps provided a reliable lower limit of the kill-zone volume.