Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

Surgical Planning Laboratory

The Abstract Database hosted by SPL

All Abstracts | Upload | Advanced Search | Gallery View | Download Statistics | Help | Import | Log in

BOLD MRI of Human Placenta and Fetuses under Maternal Hyperoxygenation in Growth Restricted Twin Pregnancies

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publication Date:
May-2016
Citation:
The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P5825.
Appears in Collections:
ISMRM
Sponsors:
P41 EB015898/EB/NIBIB NIH HHS/United States
R01 EB017337/EB/NIBIB NIH HHS/United States
U01 HD087211/HD/NICHD NIH HHS/United States
Generated Citation:
Luo J., Turk E.A., Bibbo C., Gagoski B., Vangel M., Tempany-Afdhal C.M., Malpica N., Palanisamy A., Adalsteinsson E., Robinson J.N., Grant P.E. BOLD MRI of Human Placenta and Fetuses under Maternal Hyperoxygenation in Growth Restricted Twin Pregnancies. The International Society for Magnetic Resonance in Medicine 24th Scientific Meeting & Exhibition, 2016 May, Singapore. P5825.
Export citation:
Google Scholar: link

Adequate oxygen transport across the placenta from mother to fetus is critical for fetal growth and development. In this pilot study, BOLD MRI with maternal hyperoxygenation show great potential in differentiating IUGR fetuses from controls. Not only the placentae show significant difference in rate of oxygen uptake, fetal organs also have distinct response to exposure to hyperoxia. Differences between fetal brain and liver responses to hyperoxygenation are observed in some cases, which might suggest variations in fetal hemodynamic autoregulation.