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MRI-based Temperature Analysis of Transcranial MRI-guided Focused Ultrasound Surgery for Functional Neurosurgery
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Institution: |
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. 2MR-Center, University Children’s Hospital Zurich, Zurich, Switzerland. 3Department of Functional Neurosurgery, University Hospital Zurich, Zurich, Switzerland. 4InSightec, Ltd., Tirat Carmel, Israel. |
Publication Date: |
May-2010 |
Citation: |
The International Society for Magnetic Resonance in Medicine 18th Scientific Meeting & Exhibition, 2010, Stockholm, Sweden. |
Appears in Collections: |
ISMRM |
Sponsors: |
NIH Grant RC2NS069413 |
Generated Citation: |
McDannold N.J., Werner B., Jeanmonod D., Zadicario E., Schmidt R., Martin E. MRI-based Temperature Analysis of Transcranial MRI-guided Focused Ultrasound Surgery for Functional Neurosurgery. The International Society for Magnetic Resonance in Medicine 18th Scientific Meeting & Exhibition, 2010, Stockholm, Sweden. |
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Previously, initial findings in three glioma patients treated with a transcranial MRI-guided focused ultrasound (TcMRgFUS) system were described1,2. This system uses acoustic models, geometric and density information derived from CT scans, and a phased array transducer to correct for skull-induced aberrations of the ultrasound beam to enable noninvasive thermal ablation in the brain without overheating the skull3,4. Here we report on MRI-based temperature analysis obtained in treatments in a larger patient group with an upgraded version of the system to further characterize its safety profile with respect to skull heating.
Additional Material
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ISMRM_2010_McDannolds-fig1.jpg (256.438kB)