Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

Surgical Planning Laboratory

The Abstract Database hosted by SPL

All Abstracts | Upload | Advanced Search | Gallery View | Download Statistics | Help | Import | Log in

MRI-based Temperature Analysis of Transcranial MRI-guided Focused Ultrasound Surgery for Functional Neurosurgery

Institution:
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
2MR-Center, University Children’s Hospital Zurich, Zurich, Switzerland.
3Department of Functional Neurosurgery, University Hospital Zurich, Zurich, Switzerland.
4InSightec, Ltd., Tirat Carmel, Israel.
Publication Date:
May-2010
Citation:
The International Society for Magnetic Resonance in Medicine 18th Scientific Meeting & Exhibition, 2010 May, Sweden.
Appears in Collections:
ISMRM
Sponsors:
RC2 NS069413/NS/NINDS NIH HHS/United States
Generated Citation:
McDannold N., Werner B., Jeanmonod D., Zadicario E., Schmidt R., Martin E. MRI-based Temperature Analysis of Transcranial MRI-guided Focused Ultrasound Surgery for Functional Neurosurgery. The International Society for Magnetic Resonance in Medicine 18th Scientific Meeting & Exhibition, 2010 May, Sweden.
Downloaded: 177 times. [view map]
Paper: Download, View online
Export citation:
Google Scholar: link

Previously, initial findings in three glioma patients treated with a transcranial MRI-guided focused ultrasound (TcMRgFUS) system were described1,2. This system uses acoustic models, geometric and density information derived from CT scans, and a phased array transducer to correct for skull-induced aberrations of the ultrasound beam to enable noninvasive thermal ablation in the brain without overheating the skull3,4. Here we report on MRI-based temperature analysis obtained in treatments in a larger patient group with an upgraded version of the system to further characterize its safety profile with respect to skull heating.

Additional Material
1 File (256.438kB)
ISMRM_2010_McDannolds-fig1.jpg (256.438kB)