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Evaluating the Role of PIRADS V2 and TRUSgBX for Improving Detection of Clinically Significant Prostate Cancer at Radical Prostatectomy
Institution: |
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. 2Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. 3Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. |
Publication Date: |
Jun-2018 |
Citation: |
The International Society for Magnetic Resonance in Medicine 26th Scientific Meeting & Exhibition, 2018 Jun, Paris, France. |
Appears in Collections: |
ISMRM |
Sponsors: |
R25 CA089017/CA/NCI NIH HHS/United States P41 EB015898/EB/NIBIB NIH HHS/United States |
Generated Citation: |
Ziaei A., Alessandrino F., Vangel M., Kapur T., Tempany C.M., Fennessy F.M. Evaluating the Role of PIRADS V2 and TRUSgBX for Improving Detection of Clinically Significant Prostate Cancer at Radical Prostatectomy. The International Society for Magnetic Resonance in Medicine 26th Scientific Meeting & Exhibition, 2018 Jun, Paris, France. |
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Transrectal ultrasound guided prostate biopsy (TRUSgBX) is a common diagnostic test for prostate cancer (PCa), which is known to have significant limitations [1-4] . Multiparametric MRI (mp-MRI) guided target biopsy methods have been shown to out-perform TRUSgBX for detection and diagnosis of clinically significant PCa (csPCa) [5-7], defined as presence of Gleason pattern > 4 and/or tumor volume> 0.5 ccs, and to reduce detection of indolent cancers [8] . We sought to determine the role of PIRADS V2 in conjunction with TRUSgBX to predict presence of csPCa.