Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

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Single-shot and Readout Segmented EPI: Geometric Fidelity of 3T Prostate DWI

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publication Date:
May-2014
Citation:
The International Society for Magnetic Resonance in Medicine 22nd Scientific Meeting & Exhibition, 2014 May, Milan, Italy.
Appears in Collections:
ISMRM
Sponsors:
R01 CA160902/CA/NCI NIH HHS/United States
R01 EB010195/EB/NIBIB NIH HHS/United States
R01 CA111288/CA/NCI NIH HHS/United States
P41 EB015898/EB/NIBIB NIH HHS/United States
Generated Citation:
Fedorov A., Tuncali K., Panych L.P., Fairhurst J., Tempany C.M., Maier S.E. Single-shot and Readout Segmented EPI: Geometric Fidelity of 3T Prostate DWI. The International Society for Magnetic Resonance in Medicine 22nd Scientific Meeting & Exhibition, 2014 May, Milan, Italy.
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Diffusion-Weighted Imaging (DWI) and DWI-derived Apparent Diffusion Coefficient (ADC) maps provide superior detection and visualization of Prostate Cancer (PCa)1. Commonly used Echo-Planar Imaging (EPI) sequences, however, are sensitive to local B0 inhomogeneities that often occur at tissue interfaces. In prostate imaging, severe distortions result from the presence of air in the rectum (i.e., air-filled endorectal coils, or rectal gas). This renders their use during image-guided prostate interventions difficult. Recently introduced segmented EPI sequences2 reduce such susceptibility distortions. In this study we evaluate and compare DWI geometric fidelity of the standard single-shot and readout segmented EPI sequences in a cohort of clinical patients undergoing 3T MRI-guided prostate biopsy.