NAC Neuroimage Analysis Center: Core Projects

White Matter Architecture from DT-MRI

People

Principal Investigator: Carl-Fredrik Westin, Ph.D.

Research

This core is focused on the development of novel filtering, segmentation, and tractography methods for use with DT-MRI data. The specific clinical objectives of this project are to detect and to localize white matter brain abnormalities in schizophrenia using DT-MR imaging techniques and post-processing techniques. To resolve these issues, we are developing

In addition to supporting the specific needs in this core, these tools will be directly applicable to early detection of white matter damage in the developing infant brain, to exploration and characterization of white matter disruptions caused by MS lesions, and visualization of important white matter tracts during neurosurgical procedures (e.g. the cortical spinal tract connecting to the primary and secondary motor cortex).

More information

More in-depth information about the NAC's White Matter Architecture from DT-MRI core.

Relevant Publications

Identification of translational displacements between N-dimensional data sets using the high order SVD and phase correlation.
W. Scott Hoge, Carl-Fredrik Westin
IEEE Transactions on Image Processing, 2004
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Clustering Fiber Tracts Using Normalized Cuts.
A. Brun, H. Knutsson, H. J. Park, M. E. Shenton, C.-F. Westin
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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Interface Detection in DTMRI.
L. O'Donnell, W. E. L. Grimson, C.-F. Westin
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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Anisotropic Interpolation of DT-MRI Data.
C. A. Castano-Moraga, M. A. Rodrigues-Florido, L. Alvarez, C.-F. Westin, J. Ruiz-Alzola
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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Robust Generalized Total Least Squares Iterative Closest Point Registration.
R. San-Jose, A. Brun, C.-F. Westin
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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Bias in Resampling-Based Thresholding of Statistical Maps in fMRI.
O. Friman, C.-F. Westin
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004

An Analysis Tool for Quantification of Diffusion Tensor Imaging.
H.-J. Park, M. E. Shenton, C.-F. Westin
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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3D Bayesian Regularization of Diffusion Tensor MRI using Multivariate Gaussian Markov Random Fields.
M. Martin-Fernandez, C.-F. Westin, C. Alberola-Lopez
Seventh International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI'04), Rennes - Saint Malo, France
2004
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White Matter Hemisphere Asymmetries in Healthy Subjects and in Schizophrenia: A Diffusion Tensor MRI Study.
H. J. Park, C.-F. Westin, M. Kubicki, S. E. Maier, M. Niznikiewicz, A. Baer, M. Frumin, R. Kikinis, F. A. Jolesz, R. W. McCarley, M. E. Shenton
Neuroimage, 2004
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Subspace Models for Functional MRI Data Analysis.
O. Friman
ISBI'04, Arlington, VA, USA
2004
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Method for Combining Information from White matter Fiber Tracking and Gray Matter Parcellation.
H. J. Park, M. Kubicki, C.-F. Westin, I. F. Talos, A. Brun, S. Pieper, R. Kikinis, F. A. Jolesz, R. W. McCarley, M. E. Shenton
American Journal of Neuroradiology, 2004
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Biexponential Diffusion Tensor Analysis of Human Brain Diffusion Data.
S. E. Maier, S. Vajapeyam, H. Mamata, C.-F. Westin, F. A. Jolesz, R. V. Mulkern
Magnetic Resonance in Medicine, 2004
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Comparison of Single-shot Echo-planar and Line Scan Protocols for Diffusion Tensor Imaging.
M. Kubicki, S. E. Maier, C.-F. Westin, H. Mamata, H. Ersner-Hershfield, R. San-Jose Estepar, R. Kikinis, F. A. Jolesz, R. W. McCarley, M. E. Shenton
Academic Radiology, 2004
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Shape of the Caudate Nucleus and its Cognitive Correlates in Neuroleptic-Naive Schizotypal Personality Disorder.
J. J. Levitt, C.-F. Westin, P. G. Nestor, R. San-Jose Estepar, C. C. Dickey, M. M. Voglmaier, L. J. Seidman, R. Kikinis, F. A. Jolesz, R. W. McCarley, M. E. Shenton
Biological Psychiatry, 2004
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Additional Publications Related to NAC Research

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