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Two Solutions for Registration of Ultrasound to MRI for Image-guided Prostate Interventions

1Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada.
2Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA.
IEEE Engineering in Medicine and Biology Society EMBS 2012
Publication Date:
Conf Proc IEEE Eng Med Biol Soc
Volume Number:
Conf Proc IEEE Eng Med Biol Soc. 2012 Aug;2012:1129-32.
PubMed ID:
Brachytherapy, Biomedical Imaging, Magnetic resonance imaging
Appears in Collections:
NCIGT, Prostate Group, SLICER, SPL
P41 EB015898/EB/NIBIB NIH HHS/United States
P41 RR019703/RR/NCRR NIH HHS/United States
R01 CA111288/CA/NCI NIH HHS/United States
U01 CA151261/CA/NCI NIH HHS/United States
Generated Citation:
Moradi M., Janoos F., Fedorov A., Risholm P., Kapur T., Wolfsberger L.D., Nguyen P.L., Tempany C.M., Wells III W.M. Two Solutions for Registration of Ultrasound to MRI for Image-guided Prostate Interventions. Conf Proc IEEE Eng Med Biol Soc. 2012 Aug;2012:1129-32. PMID: 23366095. PMCID: PMC3655766.
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Ultrasound-guided prostate interventions could benefit from incorporating the radiologic localization of the tumor which can be acquired from multiparametric MRI. To enable this integration, we propose and compare two solutions for registration of T2 weighted MR images with transrectal ultrasound. Firstly, we propose an innovative and practical approach based on deformable registration of binary label maps obtained from manual segmentation of the gland in the two modalities. This resulted in a target registration error of 3.6±1.7 mm. Secondly, we report a novel surface-based registration method that uses a biomechanical model of the tissue and results in registration error of 3.2±1.3 mm. We compare the two methods in terms of accuracy, clinical use and technical limitations.

Additional Material
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Moradi-IMBS2012-fig2.jpg (149.894kB)