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Multimodal Imaging for Improved Diagnosis and Treatment of Cancers

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
John Wiley & Sons, Inc.
Publication Date:
Volume Number:
Issue Number:
Cancer. 2015 Mar 15;121(6):817-27.
PubMed ID:
brain tumor, interventional magnetic resonance imaging, intraoperative monitoring, lung cancer, mass spectroscopy, multimodal imaging, neuroimaging, neuronavigation, prostate biopsy, prostate cancer
Appears in Collections:
NA-MIC, NCIGT, Prostate Group, SLICER, SPL
P01 CA067165/CA/NCI NIH HHS/United States
P41 EB015898/EB/NIBIB NIH HHS/United States
P41 RR019703/RR/NCRR NIH HHS/United States
R01 AG019513/AG/NIA NIH HHS/United States
R01 CA111288/CA/NCI NIH HHS/United States
R01 CA120528/CA/NCI NIH HHS/United States
R01 CA160902/CA/NCI NIH HHS/United States
R21 CA156943/CA/NCI NIH HHS/United States
R25 CA089017/CA/NCI NIH HHS/United States
U41 RR019703/RR/NCRR NIH HHS/United States
Generated Citation:
Tempany C.M., Jayender J., Kapur T., Bueno R., Golby A., Agar N., Jolesz F.A. Multimodal Imaging for Improved Diagnosis and Treatment of Cancers. Cancer. 2015 Mar 15;121(6):817-27. PMID: 25204551. PMCID: PMC4352132.
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The authors review methods for image-guided diagnosis and therapy that increase precision in the detection, characterization, and localization of many forms of cancer to achieve optimal target definition and complete resection or ablation. A new model of translational, clinical, image-guided therapy research is presented, and the Advanced Multimodality Image-Guided Operating (AMIGO) suite is described. AMIGO was conceived and designed to allow for the full integration of imaging in cancer diagnosis and treatment. Examples are drawn from over 500 procedures performed on brain, neck, spine, thorax (breast, lung), and pelvis (prostate and gynecologic) areas and are used to describe how they address some of the many challenges of treating brain, prostate, and lung tumors.

Additional Material
1 File (230.617kB)
Tempany-Cancer2015-fig3.jpg (230.617kB)