Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

Surgical Planning Laboratory

The Publication Database hosted by SPL

All Publications | Upload | Advanced Search | Gallery View | Download Statistics | Help | Import | Log in

Multi-slice-to-volume Registration for MRI-guided Transperineal Prostate Biopsy

Institution:
1School of Computing, Queen's University, Kingston, Canada, helen@cs.queensu.ca.
2Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publisher:
Springer
Publication Date:
May-2015
Journal:
Int J Comput Assist Radiol Surg
Volume Number:
10
Issue Number:
5
Pages:
563-72
Citation:
Int J Comput Assist Radiol Surg. 2015 May;10(5):563-72.
PubMed ID:
25193145
PMCID:
PMC4412811
Keywords:
Prostate biopsy, Target localization, MRI-guidance, Image registration
Appears in Collections:
Prostate Group, NCIGT, SLICER
Sponsors:
P41 EB015898/EB/NIBIB NIH HHS/United States
P41 RR019703/RR/NCRR NIH HHS/United States
R01 CA111288/CA/NCI NIH HHS/United States
Generated Citation:
Xu H., Lasso A., Fedorov A., Tuncali K., Tempany C.M., Fichtinger G. Multi-slice-to-volume Registration for MRI-guided Transperineal Prostate Biopsy. Int J Comput Assist Radiol Surg. 2015 May;10(5):563-72. PMID: 25193145. PMCID: PMC4412811.
Downloaded: 450 times. [view map]
Paper: Download, View online
Export citation:
Google Scholar: link

PURPOSE: Prostate needle biopsy is a commonly performed procedure since it is the most definitive form of cancer diagnosis. Magnetic resonance imaging (MRI) allows target-specific biopsies to be performed. However, needle placements are often inaccurate due to intra-operative prostate motion and the lack of motion compensation techniques. This paper detects and determines the extent of tissue displacement during an MRI-guided biopsy so that the needle insertion plan can be adjusted accordingly. METHODS: A multi-slice-to-volume registration algorithm was developed to align the pre-operative planning image volume with three intra-operative orthogonal image slices of the prostate acquired immediately before needle insertion. The algorithm consists of an initial rigid transformation followed by a deformable step. RESULTS: A total of 14 image sets from 10 patients were studied. Based on prostate contour alignment, the registrations were accurate to within 2 mm. CONCLUSION: This algorithm can be used to increase the needle targeting accuracy by alerting the clinician if the biopsy target has moved significantly prior to needle insertion. The proposed method demonstrated feasibility of intra-operative target localization and motion compensation for MRI-guided prostate biopsy.

Additional Material
1 File (42.322kB)
Xu-IJCARS2015-fig4.jpg (42.322kB)