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SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research

Institution:
1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
2Isomics, Inc., Cambridge, MA, USA.
3University of Chicago, Chicago, IL, USA.
4INRIA Sophia-Antipolis, Biot, France.
5University of Iowa, Iowa City, IA, USA.
Publisher:
HighWire
Publication Date:
Nov-2017
Journal:
Cancer Res
Volume Number:
77
Issue Number:
21
Pages:
e101-e103
Citation:
Cancer Res. 2017 Nov 1;77(21):e101-e103.
PubMed ID:
29092950
Appears in Collections:
NAC, LMI, NA-MIC, NCIGT, SLICER, SPL
Sponsors:
U01 CA199459/CA/NCI NIH HHS/United States
P41 EB015898/EB/NIBIB NIH HHS/United States
P41 EB015902/EB/NIBIB NIH HHS/United States
R01 MH074794/MH/NIMH NIH HHS/United States
R01 MH097979/MH/NIMH NIH HHS/United States
U54 EB005149/EB/NIBIB NIH HHS/United States
Generated Citation:
Norton I., Essayed W.I., Zhang F., Pujol S., Yarmarkovich A., Golby A.J., Kindlmann G., Wasserman D., Estepar R.S.J., Rathi Y., Pieper S., Kikinis R., Johnson H.J., Westin C-F., O'Donnell L.J. SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research. Cancer Res. 2017 Nov 1;77(21):e101-e103. PMID: 29092950.
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Diffusion MRI (dMRI) is the only noninvasive method for mapping white matter connections in the brain. We describe SlicerDMRI, a software suite that enables visualization and analysis of dMRI for neuroscientific studies and patient-specific anatomic assessment. SlicerDMRI has been successfully applied in multiple studies of the human brain in health and disease, and here, we especially focus on its cancer research applications. As an extension module of the 3D Slicer medical image computing platform, the SlicerDMRI suite enables dMRI analysis in a clinically relevant multimodal imaging workflow. Core SlicerDMRI functionality includes diffusion tensor estimation, white matter tractography with single and multi-fiber models, and dMRI quantification. SlicerDMRI supports clinical DICOM and research file formats, is open-source and cross-platform, and can be installed as an extension to 3D Slicer (www.slicer.org). More information, videos, tutorials, and sample data are available at dmri.slicer.org.

Additional Material
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Norton-CancerRes2017-fig1.jpg (98.734kB)