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Harvard Brain Atlas: A Teaching and Visualization Tool

Department of Psychiatry, Harvard Medical School, VAMC, Brockton, MA, USA.
Biomedical Visualization
Publication Date:
Proceedings of the 1995 Biomedical Visualization 1995 Jun; p. 10-17.
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Shenton M.E., Kikinis R., McCarley R.W., Saiviroonpom P., Hokama H.H., Robatino A., Metcalf D., Wible C.G., Portas C.M., Iosifescu D.V., Domino R., Goldstein J.M., Jolesz F.A. Harvard Brain Atlas: A Teaching and Visualization Tool. Proceedings of the 1995 Biomedical Visualization 1995 Jun; p. 10-17.
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We here present initial data from a computerized three-dimensional (30) human brain atlas project that employs automated segmentation methods, 30 slice editing techniques, region of interest definitions based on neuroanatomical knowledge, and 30 surface rendering techniques. For illustrative purposes, we show 30 representations of cerebral cortical gray matter (subdivided by lobe), cerebellum, corpus callosum, basal ganglia structures, limbic system structures, eyes and optic chiasm, and the ventricular system. Part of the white matter, including the corticospinal tract, is also reconstructed in 30. This digitized human brain atlas will be expanded and later used to automatically register new MR data sets in order to assess 30 volumes of interest. Currently, it serves as a powerful teaching tool, since spatial relationships among neuroanatomical structures can be more readily envisioned when the user is able to view and rotate the structures in 30 space, and where each element of the brain atlas is associated with a name tag that is displayed by a user-controlled pointer.