Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

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Diffusion Tensor and Functional MRI Fusion with Anatomical MRI for Image-guided Neurosurgery

Institution:
1Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA.
2Division of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA.
3Laboratory for Mathematical Imaging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA.
4Surgical Planning Laboratory, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA.
Publisher:
Med Image Comput Comput Assist Interv. MICCAI 2003
Publication Date:
Nov-2003
Volume Number:
6
Issue Number:
Pt 1
Pages:
407-15
Citation:
Int Conf Med Image Comput Comput Assist Interv. 2003 Nov;6(Pt 1):407-15.
Keywords:
Diffusion Tensor, Functional MRI (fMRI), Image-guided Neurosurgery
Appears in Collections:
SPL, CNI, CRL, LMI, MIPG, NAC, NCIGT, SLICER
Generated Citation:
Talos I-F., O'Donnell L., Westin C-F., Warfield S.K., Wells III W.M., Yoo S-S., Panych L.P., Golby A.J., Mamata H., Maier S.E., Ratiu P., Guttmann C.R.G., Black P.M., Jolesz F.A., Kikinis R. Diffusion Tensor and Functional MRI Fusion with Anatomical MRI for Image-guided Neurosurgery. Int Conf Med Image Comput Comput Assist Interv. 2003 Nov;6(Pt 1):407-15.
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In order to achieve its main goal of maximal tumor removal while avoiding postoperative neurologic deficits, neuro-oncological surgery is strongly dependent on image guidance. Among all currently available imaging modalities, MRI provides the best anatomic detail and is highly sensitive for intracranial pathology. However, conventional MRI does not detect the exact location of white matter tracts or areas of cortical activation. This essential information can be obtained non-invasively by means of diffusion tensor MRI (DT-MRI) and functional MRI (fMRI) respectively. Here we present our initial experience with fMRI and DT-MRI for surgical planning and guidance in ten brain tumor cases.

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