Surgical Planning Laboratory - Brigham & Women's Hospital - Boston, Massachusetts USA - a teaching affiliate of Harvard Medical School

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Three-dimensional reconstruction and surgical navigation in pediatric epilepsy surgery

Chabrerie A.1, Ozlen F.1, Nakajima S.1, Leventon M.E.3, Atsumi H.1, Grimson W.E.L.3, Keeve E.1, Helmers S.1, Riviello J.1, Holmes G.1, Duffy F.1, Jolesz F.A.1, Kikinis R.1, Black P.M.2
Institution:
1Surgical Planning Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.
2Divison if Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.
3Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge MA, USA.
Publisher:
Pediatr Neurosurg
Publication Date:
Dec-1997
Citation:
Pediatr Neurosurg. 1997 Dec;27(6):304-10.
PubMed ID:
9655145
Keywords:
epilepsy surgery, 3D reconstruction, subdural grids and strips
Appears in Collections:
SPL, NCIGT
Sponsors:
P01 AGO4953-14 (AG) funded by NIA
P01 CA 67165-01A1 (CA) funded by NCI
R01 CA 46227-08 (CA) funded by NCI
Generated Citation:
Chabrerie A., Ozlen F., Nakajima S., Leventon M.E., Atsumi H., Grimson W.E.L., Keeve E., Helmers S., Riviello J., Holmes G., Duffy F., Jolesz F.A., Kikinis R., Black P.M. Three-dimensional reconstruction and surgical navigation in pediatric epilepsy surgery. Pediatr Neurosurg. 1997 Dec;27(6):304-10. PMID: 9655145.
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We have used MRI-based three-dimensional (3D) reconstruction and a real-time, frameless, stereotactic navigation device to facilitate the removal of seizure foci in children suffering from intractable epilepsy. Using this system, the location of subdural grid and strip electrodes is recorded on the 3D model to facilitate focus localization and resection. Ten operations were performed, including 2 girls and 8 boys ranging in age from 3 to 17, during which 3D reconstruction and surgical instrument tracking navigation was used. In all the cases, the patients tolerated the procedure well and showed no postoperative neurological deficits. We believe this to be a valuable tool for a complete and safe resection of seizure foci, thereby reducing the incidence of postoperative neurological deficits and significantly improving the overall quality of life of the patients.

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